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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
MGI:2180781
18 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc8b1em1(IMPC)J/Slc8b1em1(IMPC)J
C57BL/6NJ-Slc8b1em1(IMPC)J/J 		abnormal coat appearance J:211773
abnormal sleep behavior J:211773
decreased exploration in new environment J:211773
impaired righting response J:211773
Slc8b1tm1c(EUCOMM)Wtsi/Slc8b1tm1c(EUCOMM)Wtsi
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: 129S4/SvJaeSor * C57BL/6N * FVB/N 		abnormal sarcomere morphology J:325413
cardiac fibrosis J:325413
cardiac hypertrophy J:325413
congestive heart failure J:325413
decreased heart rate J:325413
decreased ventricle muscle contractility J:325413
dilated heart left ventricle J:325413
dilated mitochondrion J:325413
increased heart weight J:325413
increased myocardial fiber size J:325413
irregular heartbeat J:325413
premature death J:325413
prolonged PR interval J:325413
prolonged QRS complex duration J:325413
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory