Atpaf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1
MGI:2180560

25 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Atpaf1^em1Cya/Atpaf1^em1Cya involves: C57BL/6N	abnormal cardiovascular system physiology	J:347150
	abnormal cellular respiration	J:347150
	abnormal enzyme/coenzyme activity	J:347150
	abnormal enzyme/coenzyme level	J:347150
	abnormal mitochondrial ATP synthesis coupled electron transport	J:347150
	abnormal mitochondrial crista morphology	J:347150
	abnormal mitochondrial physiology	J:347150
	abnormal myocardial fiber mitochondrial morphology	J:347150
	abnormal oxidative phosphorylation	J:347150
	normal behavior/neurological phenotype	J:347150
	cardiac fibrosis	J:347150
	cardiac hypertrophy	J:347150
	congestive heart failure	J:347150
	decreased body size	J:347150
	decreased heart left ventricle muscle contractility	J:347150
	decreased mitochondrial size	J:347150
	dilated cardiomyopathy	J:347150
	dilated mitochondrion	J:347150
	impaired autophagy	J:347150
	increased circulating lactate level	J:347150
	increased heart weight	J:347150
	increased myocardial fiber apoptosis	J:347150
	increased myocardial fiber size	J:347150
	oxidative stress	J:347150
	slow postnatal weight gain	J:347150

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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