Atpaf1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atpaf1^em1Cya
• Name: ATP synthase mitochondrial F1 complex assembly factor 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7792241
• Synonyms: Atpaf1^em1Cya, Atpaf1-KO
• Gene: Atpaf1 Location: Chr4:115642025-115669120 bp, + strand Genetic Position: Chr4, 53.06 cM
• Alliance: Atpaf1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2~4 was selected as target site. Semi-quantitative RT-PCR demonstrated absence of mRNA expression. Western blot analysis confirmed the absence of protein in heart, brain, liver, and skeletal muscle samples from homozygous mutant mice. (J:326541)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atpaf1 Mutation: 19 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 2 reference(s)