Lgi4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lgi4
leucine-rich repeat LGI family, member 4
MGI:2180197

34 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lgi4^clp/Lgi4^clp C57BL/6J-Lgi4^clp/J	abnormal axon morphology	J:11392
	abnormal digit morphology	J:24743
	abnormal forelimb morphology	J:11392, J:24743
	abnormal hindlimb morphology	J:11392
	abnormal limb morphology	J:11392, J:105260
	abnormal locomotor behavior	J:11392
	abnormal long bone morphology	J:11392
	abnormal maternal nurturing	J:11392
	abnormal myelin sheath morphology	J:11392, J:24743
	abnormal myelination	J:11392, J:24743
	abnormal nervous system morphology	J:11392, J:105260
	abnormal posture	J:11392, J:24743, J:105260
	abnormal sciatic nerve morphology	J:105260
	abnormal sexual interaction	J:11392
	decreased body size	J:11392
	decreased diameter of radius	J:11392
	decreased diameter of ulna	J:11392
	impaired righting response	J:11392
	normal muscle phenotype	J:11392
	postnatal lethality, incomplete penetrance	J:11392
Lgi4^clp/Lgi4^clp involves: C57BL/6J	demyelination	J:158973
Lgi4^clp/Lgi4^clp involves: C57BL/6J * FVB/N	abnormal myelination	J:208847
Lgi4^{tm1.1(KOMP)Vlcg}/Lgi4⁺ C57BL/6N-Lgi4^{tm1.1(KOMP)Vlcg}/Ucd	abnormal behavior	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
	microcephaly	J:211773
	syndactyly	J:211773
Lgi4^{tm1.1(KOMP)Vlcg}/Lgi4^{tm1.1(KOMP)Vlcg} C57BL/6N-Lgi4^{tm1.1(KOMP)Vlcg}/Ucd	microcephaly	J:211773
	preweaning lethality, complete penetrance	J:211773
	syndactyly	J:211773
Lgi4^tm1.1Jrb/Lgi4^tm1.1Jrb H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S4/SvJaeSor * C57BL/6J * CBA/J	demyelination	J:158973
Lgi4^tm1.1Jrb/Lgi4^tm1.1Jrb Tg(Dhh-cre)1Mejr/0 involves: 129S4/SvJaeSor * FVB/N	demyelination	J:158973
Lgi4^tm1Sjm/Lgi4^tm1Sjm involves: C57BL/6 * SJL	abnormal forelimb morphology	J:166449
	abnormal glial cell morphology	J:166449
	abnormal glial cell physiology	J:166449
	abnormal PNS glial cell morphology	J:166449
	abnormal Schwann cell morphology	J:166449
	abnormal sciatic nerve morphology	J:166449
	decreased body size	J:166449
	decreased body weight	J:166449
	demyelination	J:166449
	neonatal lethality, incomplete penetrance	J:166449
	postnatal growth retardation	J:166449

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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