Havcr2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Havcr2
hepatitis A virus cellular receptor 2
MGI:2159682

13 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Havcr2^{tm1b(KOMP)Wtsi}/Havcr2^{tm1b(KOMP)Wtsi} C57BL/6N-Havcr2^{tm1b(KOMP)Wtsi}/Ucd	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	enlarged heart	J:211773
	increased spleen weight	J:211773
Havcr2^tm1Bmed/Havcr2^tm1Bmed B6.Cg-Havcr2^tm1Bmed	abnormal CD8-positive, alpha-beta T cell physiology	J:189839
	decreased activation-induced cell death of T cells	J:189839
	decreased interferon-gamma secretion	J:189839
	decreased susceptibility to Orthomyxoviridae infection	J:189839
	decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:189839
	decreased susceptibility to weight loss	J:189839
	decreased T cell proliferation	J:189839
Havcr2^tm1Tbs/Havcr2^tm1Tbs C.Cg-Havcr2^tm1Tbs	normal immune system phenotype	J:86260
Havcr2^tm1Vlcg/Havcr2^tm1Vlcg B6.129-Havcr2^tm1Vlcg	decreased interferon-gamma secretion	J:209885
Havcr2^tm1Vlcg/Havcr2^tm1Vlcg B6.129-Havcr2^tm1Vlcg	decreased T cell number	J:209885

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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