Polq Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Polq
polymerase (DNA directed), theta
MGI:2155399

10 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Polq^chaos1/Polq^chaos1 involves: C3HeB/FeJ * C57BL/6J	chromosome breakage	J:82700
Polq^em1(IMPC)Mbp/Polq^em1(IMPC)Mbp C57BL/6N-Polq^em1(IMPC)Mbp/MbpMmucd	abnormal spleen morphology	J:211773
	increased grip strength	J:211773
	small spleen	J:211773
Polq^tm1Jcs/Polq^tm1Jcs involves: 129S4/SvJae * C57BL/6J	abnormal somatic hypermutation frequency	J:103365
Polq^tm1Jow/Polq^tm1Jow involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	abnormal B cell physiology	J:101409
	abnormal somatic hypermutation frequency	J:101409
	decreased IgG1 level	J:101409
	decreased IgG level	J:101409
	decreased IgM level	J:101409
	decreased immunoglobulin level	J:101409
Polq^tm2Jow/Polq^tm2Jow involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal somatic hypermutation frequency	J:115989

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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