Sec63 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sec63
SEC63 homolog, protein translocation regulator
MGI:2155302

16 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sec63^tm1.1Som/Sec63^tm1.1Som involves: 129 * C57BL/6	embryonic lethality, complete penetrance	J:188763
Sec63^{tm1b(EUCOMM)Hmgu}/Sec63⁺ C57BL/6N-Sec63^{tm1b(EUCOMM)Hmgu}/Bay	abnormal vibrissa morphology	J:211773
	absent vibrissae	J:211773
	decreased bone mineral density	J:211773
	decreased lymphocyte cell number	J:211773
	increased circulating alanine transaminase level	J:211773
	increased neutrophil cell number	J:211773
Sec63^{tm1b(EUCOMM)Hmgu}/Sec63^{tm1b(EUCOMM)Hmgu} C57BL/6N-Sec63^{tm1b(EUCOMM)Hmgu}/Bay	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Sec63^tm1Som/Sec63^tm1Som Tg(CAG-cre/Esr1)1Lbe/0 involves: 129 129S1/Sv * 129X1/SvJ * C57BL/6	liver cyst	J:188763
	premature death	J:188763
Sec63^tm1Som/Sec63^tm1Som Tg(Cdh16-cre)91Igr/0 involves: 129 * C57BL/6 * ICR	abnormal loop of Henle ascending limb thick segment morphology	J:188763
	dilated kidney collecting duct	J:188763
	increased blood urea nitrogen level	J:188763
	kidney cyst	J:188763
	premature death	J:188763

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23