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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dph1
diphthamide biosynthesis 1
MGI:2151233
47 phenotypes from 3 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Dph1tm1.1Cmch/Dph1tm1.1Cmch
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
abnormal tongue position J:214744
absent palatine bone J:214744
cleft palate J:214744
edema J:214744
fetal growth retardation J:214744
mandible hypoplasia J:214744
neonatal lethality, complete penetrance J:214744
palatal shelves fail to meet at midline J:214744
pallor J:214744
short mandible J:214744
small cranium J:214744
Dph1tm1.1Cmch/Dph1tm1.1Cmch
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
cleft palate J:214744
decreased cranium length J:214744
postnatal lethality, incomplete penetrance J:214744
round face J:214744
short mandible J:214744
short Meckel's cartilage J:214744
short nasal bone J:214744
Dph1tm1.1Cmch/Dph1tm1.1Cmch
Mesp1tm2(cre)Ysa/Mesp1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
normal craniofacial phenotype J:214744
postnatal lethality, incomplete penetrance J:214744
Dph1tm1Bhr/Dph1+
involves: 129/Sv * C57BL/6
increased tumor incidence J:88090
Dph1tm1Bhr/Dph1tm1Bhr
either: 129/Sv or (involves: 129/Sv * C57BL/6)
abnormal cell cycle J:88090
abnormal craniofacial bone morphology J:88090
abnormal lung development J:88090
abnormal neural tube morphology J:88090
abnormal skeleton development J:88090
cleft palate J:88090
decreased fetal weight J:88090
embryonic growth retardation J:88090
embryonic lethality during organogenesis, incomplete penetrance J:88090
embryonic lethality, complete penetrance J:88090
hydrops fetalis J:88090
increased nucleated erythrocyte cell number J:88090
neonatal lethality, complete penetrance J:88090
preaxial polydactyly J:88090
primary atelectasis J:88090
respiratory failure J:88090
thick lung-associated mesenchyme J:88090
Dph1tm1Bhr/Dph1tm1Bhr
involves: 129S4/SvJae
abnormal cell physiology J:188600
decreased fibroblast proliferation J:188600
decreased sensitivity to induced cell death J:188600
Dph1tm1Bhr/Dph1tm2Bhr
involves: 129/Sv * C57BL/6
decreased fetal weight J:88090
embryonic growth retardation J:88090
embryonic lethality during organogenesis, incomplete penetrance J:88090
hydrops fetalis J:88090
neonatal lethality, complete penetrance J:88090
Dph1tm2Bhr/Dph1+
involves: 129/Sv * C57BL/6
increased tumor incidence J:88090
Dph1tm2Bhr/Dph1tm2Bhr
either: 129/Sv or (involves: 129/Sv * C57BL/6)
abnormal cell cycle J:88090
abnormal craniofacial bone morphology J:88090
abnormal embryo turning J:88090
abnormal eye morphology J:88090
abnormal eye pigmentation J:88090
abnormal hepatoblast morphology J:88090
abnormal lung development J:88090
abnormal neural tube morphology J:88090
abnormal skeleton development J:88090
abnormal somite development J:88090
cleft palate J:88090
decreased fetal weight J:88090
embryonic growth retardation J:88090
embryonic lethality during organogenesis, incomplete penetrance J:88090
embryonic lethality, complete penetrance J:88090
hydrops fetalis J:88090
increased nucleated erythrocyte cell number J:88090
liver degeneration J:88090
neonatal lethality, complete penetrance J:88090
preaxial polydactyly J:88090
primary atelectasis J:88090
respiratory failure J:88090
thick lung-associated mesenchyme J:88090
Dph1tm2Bhr/Dph1tm2Bhr
involves: 129S4/SvJae * C57BL/6J
abnormal tongue position J:214744
absent palatine bone J:214744
cleft secondary palate J:214744
decreased body size J:214744
decreased palatal shelf size J:214744
lethality at weaning, complete penetrance J:214744
micrognathia J:214744
palatal shelves fail to meet at midline J:214744
preaxial polydactyly J:214744
short Meckel's cartilage J:214744
small cranium J:214744

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory