Mta1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mta1
metastasis associated 1
MGI:2150037

23 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mta1^{em1(IMPC)Ccpcz}/Mta1⁺ C57BL/6NCrl-Mta1^{em1(IMPC)Ccpcz}/Ccpcz	abnormal liver morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	dilated aorta	J:211773
	increased cardiac muscle contractility	J:211773
	increased effector memory CD8-positive, alpha-beta T cell number	J:211773
	small liver	J:211773
	small seminal vesicle	J:211773
	thick ventricular wall	J:211773
Mta1^{em1(IMPC)Ccpcz}/Mta1^{em1(IMPC)Ccpcz} C57BL/6NCrl-Mta1^{em1(IMPC)Ccpcz}/Ccpcz	no spontaneous movement	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Mta1^{tm1a(EUCOMM)Wtsi}/Mta1⁺ 129S/SvEvBrd-Mta1^{tm1a(EUCOMM)Wtsi}/WtsiH	decreased caudal vertebrae number	J:175295
	increased circulating triglyceride level	J:175295
Mta1^{tm1a(EUCOMM)Wtsi}/Mta1^{tm1a(EUCOMM)Wtsi} 129S/SvEvBrd-Mta1^{tm1a(EUCOMM)Wtsi}/WtsiH	abnormal behavior	J:175295
	abnormal bone mineralization	J:175295
	decreased body weight	J:165965
	decreased caudal vertebrae number	J:175295
	decreased circulating LDL cholesterol level	J:175295
	decreased lumbar vertebrae number	J:175295
	increased sacral vertebrae number	J:175295
	thrombocytopenia	J:175295
Mta1^{tm1a(EUCOMM)Wtsi}/Mta1^{tm1a(EUCOMM)Wtsi} involves: 129S7/SvEvBrd	normal mortality/aging	J:278486
Mta1^tm1Raku/Mta1^tm1Raku involves: 129S4/SvJae	increased cellular sensitivity to ionizing radiation	J:153679
Mta1^tm1Raku/Mta1^tm1Raku involves: 129S4/SvJae * C57BL/6	abnormal retina development	J:123470
Mta1^tm1Raku/Mta1^tm1Raku involves: 129S4/SvJae * C57BL/6	normal vision/eye phenotype	J:123470

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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