Cldn16 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cldn16
claudin 16
MGI:2148742

15 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Cldn16^tm1.1Dmu/Cldn16^tm1.1Dmu involves: 129 * BALB/cJ * C57BL/6	abnormal renal calcium reabsorption	J:159706
	abnormal renal reabsorption	J:159706
	abnormal vitamin D level	J:159706
	decreased circulating magnesium level	J:159706
	decreased urine pH	J:159706
	increased circulating parathyroid hormone level	J:159706
	increased urine calcium level	J:159706
Tg(RNU6-RNAi:Cldn16)551Dago/0 involves: C57BL/6 * DBA/2	decreased bone mineral content	J:122766
	decreased bone mineral density	J:122766
	decreased circulating magnesium level	J:122766
	hypokalemia	J:122766
	hypotension	J:122766
	increased circulating aldosterone level	J:122766
	increased urine calcium level	J:122766
	increased urine magnesium level	J:122766
	increased urine potassium level	J:122766
	nephrocalcinosis	J:122766

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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