Trib2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trib2
tribbles pseudokinase 2
MGI:2145021

10 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trib2^{tm1b(KOMP)Wtsi}/Trib2⁺ C57BL/6N-Trib2^{tm1b(KOMP)Wtsi}/Bay	abnormal retina inner nuclear layer morphology	J:211773
	decreased total retina thickness	J:211773
Trib2^{tm1b(KOMP)Wtsi}/Trib2^{tm1b(KOMP)Wtsi} C57BL/6N-Trib2^{tm1b(KOMP)Wtsi}/Bay	abnormal retina inner nuclear layer morphology	J:211773
	abnormal retina outer nuclear layer morphology	J:211773
	decreased total retina thickness	J:211773
	hyperactivity	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Trib2^tm1Lex/Trib2^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased B cell number	J:82809
	decreased exploration in new environment	J:82809
	increased CD8-positive, alpha-beta T cell number	J:82809
Trib2^tm1Myam/Trib2^tm1Myam involves: 129X1/SvJ * C57BL/6	normal hematopoietic system phenotype	J:196449
Trib2^tm1Ryn/Trib2^tm1Ryn involves: C57BL/6 * CBA	no abnormal phenotype detected	J:138553

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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