Usp22 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Usp22
ubiquitin specific peptidase 22
MGI:2144157

31 phenotypes from 7 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Usp22^em14Dent/Usp22^em14Dent FVB-Usp22^em14Dent	embryonic lethality, complete penetrance	J:272613
Usp22^em25Dent/Usp22^em25Dent FVB-Usp22^em25Dent	embryonic lethality, complete penetrance	J:272613
Usp22^{Gt(RRS377)Byg}/Usp22^{Gt(RRS377)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal placenta intervillous maternal lacunae morphology	J:272613
	abnormal placental labyrinth vasculature morphology	J:272613
	embryonic lethality during organogenesis, complete penetrance	J:272613
	hypoxia	J:272613
	placental labyrinth hypoplasia	J:272613
Usp22^{Gt(XP0208)Wtsi}/Usp22^{Gt(XP0208)Wtsi} involves: 129P2/OlaHsd * C57BL/6	prenatal growth retardation	J:272613
	prenatal lethality, incomplete penetrance	J:272613
Usp22^{tm1a(KOMP)Wtsi}/Usp22⁺ C57BL/6N-Usp22^{tm1a(KOMP)Wtsi}/Wtsi	increased lean body mass	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	increased red blood cell distribution width	J:211773
Usp22^{tm1a(KOMP)Wtsi}/Usp22^{tm1a(KOMP)Wtsi} C57BL/6-Usp22^{tm1a(KOMP)Wtsi}	abnormal cell differentiation	J:233975
	abnormal cerebral cortex morphology	J:233975
	abnormal cortical plate morphology	J:233975
	abnormal intestinal enteroendocrine cell morphology	J:233975
	abnormal intestinal epithelium morphology	J:233975
	abnormal intestinal villus goblet cell morphology	J:233975
	abnormal small intestine morphology	J:233975
	abnormal stratification in cerebral cortex	J:233975
	decreased body weight	J:233975
	impaired neuron differentiation	J:233975
	increased Paneth cell number	J:233975
	normal mortality/aging	J:233975
	postnatal growth retardation	J:233975
Usp22^{tm1a(KOMP)Wtsi}/Usp22^{tm1a(KOMP)Wtsi} C57BL/6N-Usp22^{tm1a(KOMP)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Usp22^{tm1b(KOMP)Wtsi}/Usp22⁺ C57BL/6N-Usp22^{tm1b(KOMP)Wtsi}/Wtsi	abnormal gait	J:211773
	increased monocyte cell number	J:211773
Usp22^{tm1b(KOMP)Wtsi}/Usp22^{tm1b(KOMP)Wtsi} C57BL/6N-Usp22^{tm1b(KOMP)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Usp22^tm1Dfan/Usp22^tm1Dfan C57BL/6-Usp22^tm1Dfan	decreased embryo size	J:188021
	embryonic growth retardation	J:188021
	embryonic lethality during organogenesis, complete penetrance	J:188021
	increased fibroblast apoptosis	J:188021

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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