About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Smg6
SMG6 nonsense mediated mRNA decay factor
MGI:2144117
16 phenotypes from 3 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Smg6em1(IMPC)Mbp/Smg6+
C57BL/6NCrl-Smg6em1(IMPC)Mbp/Mmucd
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal startle reflex J:211773
decreased hematocrit J:211773
enlarged spleen J:211773
scaly skin J:211773
Smg6em1(IMPC)Mbp/Smg6em1(IMPC)Mbp
C57BL/6NCrl-Smg6em1(IMPC)Mbp/Mmucd
embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Smg6tm1.1Zqw/Smg6tm1.1Zqw
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * 129S4/SvJae
abnormal cell morphology J:222980
abnormal cell physiology J:222980
abnormal telomere morphology J:222980
normal cellular phenotype J:222980
Smg6tm1.2Zqw/Smg6tm1.2Zqw
involves: 129P2/OlaHsd * C57BL/6 * CBA
decreased inner cell mass proliferation J:222980
embryonic growth retardation J:222980
embryonic lethality at implantation, incomplete penetrance J:222980
prenatal lethality, complete penetrance J:222980

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory