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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dis3l
DIS3 like exosome 3'-5' exoribonuclease
MGI:2143272
13 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Dis3lem1(IMPC)Ccpcz/Dis3l+
C57BL/6NCrl-Dis3lem1(IMPC)Ccpcz/Ccpcz
abnormal kidney morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
enlarged kidney J:211773
increased eosinophil cell number J:211773
thick ventricular wall J:211773
Dis3lem1(IMPC)Ccpcz/Dis3lem1(IMPC)Ccpcz
C57BL/6NCrl-Dis3lem1(IMPC)Ccpcz/Ccpcz
preweaning lethality, complete penetrance J:211773
Dis3lem1Adki/Dis3lem1Adki
involves: C57BL/6JTar * CBA/WTar
no abnormal phenotype detected J:365445
Dis3lem2Adki/Dis3lem2Adki
involves: C57BL/6JTar * CBA/WTar
abnormal embryo morphology J:365445
abnormal translation J:365445
decreased embryo size J:365445
embryonic growth arrest J:365445
embryonic lethality between implantation and somite formation, complete penetrance J:365445

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory