C2cd3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

C2cd3
C2 calcium-dependent domain containing 3
MGI:2142166

30 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
C2cd3^em1(IMPC)Tcp/C2cd3⁺ C57BL/6N-C2cd3^em1(IMPC)Tcp/Tcp	abnormal skin morphology	J:211773
	abnormal uterus morphology	J:211773
	decreased lymphocyte cell number	J:211773
	enlarged urinary bladder	J:211773
	hyperactivity	J:211773
	increased neutrophil cell number	J:211773
C2cd3^em1(IMPC)Tcp/C2cd3^em1(IMPC)Tcp C57BL/6N-C2cd3^em1(IMPC)Tcp/Tcp	abnormal embryo size	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
C2cd3^em1Brgm/C2cd3^em1Brgm involves: C57BL/6J * C57BL/6NCrl * CD-1	abnormal cranial flexure morphology	J:308674
	abnormal developmental patterning	J:308674
	abnormal heart looping	J:308674
	exencephaly	J:308674
	pericardial edema	J:308674
C2cd3^em1Brgm/C2cd3^em1Brgm involves: C57BL/6NCrl * CD-1	abnormal cranial flexure morphology	J:308674
	abnormal developmental patterning	J:308674
	abnormal heart looping	J:308674
	abnormal primary cilium morphology	J:308674
	embryonic lethality during organogenesis, complete penetrance	J:308674
	exencephaly	J:308674
	pericardial edema	J:308674
C2cd3^em2Brgm/C2cd3^em2Brgm E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ involves: C3H * C57BL/6	abnormal cilium physiology	J:308674
	abnormal tongue morphology	J:308674
	cleft palate	J:308674
	delayed bone ossification	J:308674
C2cd3^{Gt(AG0177)Wtsi}/C2cd3^{Gt(AG0177)Wtsi} involves: 129P2/OlaHsd * C3H/He	abnormal dorsal-ventral axis patterning	J:142506
	abnormal floor plate morphology	J:142506
	absent embryonic cilia	J:142506
	embryonic lethality during organogenesis, complete penetrance	J:142506
	exencephaly	J:142506
C2cd3^hty/C2cd3^{Gt(AG0177)Wtsi} involves: 129P2/OlaHsd * C3H/He * C57BL/6	abnormal rostral-caudal body axis extension	J:142506
	embryonic lethality during organogenesis, complete penetrance	J:142506
	pericardial edema	J:142506
C2cd3^hty/C2cd3^hty involves: C3H/He * C57BL/6	abnormal cranial flexure morphology	J:142506
	abnormal direction of heart looping	J:142506
	abnormal dorsal-ventral axis patterning	J:142506
	abnormal floor plate morphology	J:142506
	abnormal left-right axis patterning	J:142506
	abnormal rostral-caudal body axis extension	J:142506
	absent embryonic cilia	J:142506
	embryonic lethality during organogenesis, complete penetrance	J:142506
	exencephaly	J:142506
	pericardial edema	J:142506
	polydactyly	J:142506
C2cd3^{tm1a(EUCOMM)Wtsi}/C2cd3^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	embryonic lethality during organogenesis, complete penetrance	J:308674
C2cd3^{tm1c(EUCOMM)Wtsi}/C2cd3^{tm1c(EUCOMM)Wtsi} E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ involves: C3H * C57BL/6	abnormal cilium physiology	J:308674
	abnormal facial morphology	J:308674
	cleft palate	J:308674
	delayed bone ossification	J:308674
	tongue hypoplasia	J:308674

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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