Pot1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pot1a
protection of telomeres 1A
MGI:2141503

24 phenotypes from 5 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pot1a^em1Blas/Pot1a^em1Blas C57BL/6NCrl-Pot1a^em1Blas	abnormal bronchus-associated lymphoid tissue morphology	J:375765
	abnormal crypts of Lieberkuhn morphology	J:375765
	abnormal intestinal epithelium morphology	J:375765
	abnormal intestine morphology	J:375765
	abnormal intracellular organelle physiology	J:375765
	abnormal lung morphology	J:375765
	abnormal testis interstitial tissue morphology	J:375765
	abnormal testis morphology	J:375765
	decreased body weight	J:375765
	decreased litter size	J:375765
	decreased small intestinal villus height	J:375765
	decreased telomere length	J:375765
	hemosiderosis	J:375765
	increased Leydig cell number	J:375765
	lung inflammation	J:375765
	pulmonary fibrosis	J:375765
	testicular atrophy	J:375765
	thick pulmonary interalveolar septum	J:375765
Pot1a^{Gt(RRA096)Byg}/Pot1a^{Gt(RRA096)Byg} involves: 129P2/OlaHsd * C57BL/6J	absent inner cell mass	J:112185
	embryonic lethality between implantation and somite formation, complete penetrance	J:112185
	prenatal lethality, complete penetrance	J:112185
Pot1a^tm1.1Schg/Pot1a^tm1.1Schg involves: 129S7/SvEvBrd * C57BL/6	decreased cell proliferation	J:112184
Pot1a^tm1Schg/Pot1a^tm1.1Schg involves: 129S7/SvEvBrd * C57BL/6	abnormal chromosome morphology	J:112184
	abnormal telomere length	J:112184
	decreased cell proliferation	J:112184
Pot1a^tm1Tdl/Pot1a^tm1Tdl involves: 129P2/OlaHsd * C57BL/6J	prenatal lethality, complete penetrance	J:112185

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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