About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hrh3
histamine receptor H3
MGI:2139279
27 phenotypes from 5 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Hrh3Eae8-r/?
B10.S-H2s/SgMcdJ
decreased susceptibility to experimental autoimmune encephalomyelitis J:34892
Hrh3Eae8-r/Hrh3Eae8-r
involves: B10.S/DvTe * SJL/J
decreased susceptibility to experimental autoimmune encephalomyelitis J:49054
Hrh3Eae8-s/?
involves: B10.S * SJL/J
increased susceptibility to experimental autoimmune encephalomyelitis J:49054
Hrh3tm1.1Jhwa/Hrh3tm1.1Jhwa
involves: C57BL/6 * C57BL/6NTac
abnormal glucose homeostasis J:174155
decreased physiological sensitivity to xenobiotic J:174155
increased circulating glucose level J:174155
Hrh3tm1Kot/Hrh3tm1Kot
involves: 129X1/SvJ * C57BL/6N
abnormal energy expenditure J:80824
decreased core body temperature J:80824
decreased locomotor activity J:80824
decreased oxygen consumption J:80824
increased circulating insulin level J:80824
increased circulating leptin level J:80824
increased susceptibility to weight gain J:80824
increased total body fat amount J:80824
insulin resistance J:80824
polyphagia J:80824
Hrh3tm1Twl/Hrh3tm1Twl
B6.129X1-Hrh3tm1Twl
impaired blood-brain barrier function J:122269
increased susceptibility to experimental autoimmune encephalomyelitis J:122269
Hrh3tm1Twl/Hrh3tm1Twl
involves: 129P2/OlaHsd
abnormal cardiovascular system physiology J:103897
abnormal synaptic norepinephrine release J:103897
normal immune system phenotype J:132140
Hrh3tm1Twl/Hrh3tm1Twl
involves: 129P2/OlaHsd * C57BL/6J
abnormal anxiety-related response J:79168
abnormal circadian temperature homeostasis J:79168
abnormal hormone level J:89633
abnormal locomotor activation J:79168
abnormal nervous system physiology J:79168
abnormal spatial learning J:89633
decreased anxiety-related response J:89633
increased anxiety-related response J:89633

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory