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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Znfx1
zinc finger, NFX1-type containing 1
MGI:2138982
14 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Znfx1em1(IMPC)J/Znfx1em1(IMPC)J
C57BL/6NJ-Znfx1em1(IMPC)J/Mmjax 		decreased grip strength J:211773
decreased total body fat amount J:211773
Znfx1em1Xua/Znfx1em1Xua
involves: C57BL/6J 		abnormal macrophage physiology J:345967
abnormal response to infection J:282875
decreased circulating interferon-gamma level J:345967
decreased circulating interleukin-12 level J:345967
decreased circulating tumor necrosis factor level J:345967
decreased interferon-alpha secretion J:282875
decreased interferon-beta secretion J:282875
decreased macrophage cytokine production J:282875
impaired autophagy J:345967
impaired macrophage phagocytosis J:345967
increased susceptibility to bacterial infection J:345967
increased susceptibility to Riboviria infection J:282875
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory