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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Med15
mediator complex subunit 15
MGI:2137379
12 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ins1tm1.1(cre)Thor/Ins1+
Med15tm1c(KOMP)Wtsi/Med15tm1c(KOMP)Wtsi
involves: C57BL/6J * C57BL/6N 		abnormal endocrine pancreas physiology J:355262
abnormal mitochondrial biogenesis J:355262
abnormal pancreatic beta cell differentiation J:355262
decreased cellular glucose uptake J:355262
decreased circulating insulin level J:355262
decreased insulin secretion J:355262
decreased mitochondrial number J:355262
normal endocrine/exocrine gland phenotype J:355262
normal growth/size/body region phenotype J:355262
impaired glucose tolerance J:355262
increased mitochondrial size J:355262
increased pancreatic beta cell proliferation J:355262
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory