57 phenotypes from 9 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pvalbtm1(cre)Arbr/Pvalb+ Slc12a6tm2.1Dlp/Slc12a6tm2.1Dlp involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	abnormal dorsal root ganglion morphology	J:217087
	impaired coordination	J:217087
Scn10atm2(cre)Jwo/Scn10a+ Slc12a6tm2.1Dlp/Slc12a6tm2.1Dlp involves: 129 * 129S6/SvEvTac * C57BL/6J	normal behavior/neurological phenotype	J:217087
Slc12a6em1Dlp/Slc12a6em1Dlp involves: C57BL/6J	abnormal nerve conduction	J:259728
	demyelination	J:259728
	impaired coordination	J:259728
Slc12a6gaxp/Slc12a6gaxp C3H/HeSnJ-Slc12a6gaxp/GrsrJ	abnormal axon morphology	J:82451
	abnormal brain morphology	J:82451
	abnormal myelination	J:82451
	ataxia	J:136097
	axonal dystrophy	J:82451
	paraparesis	J:136097
	weakness	J:136097
Slc12a6Gt(OST458419)Lex/Slc12a6Gt(OST458419)Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal gait	J:103485
	abnormal physical strength	J:103485
	decreased exploration in new environment	J:103485
	impaired coordination	J:103485
	increased coping response	J:103485
Slc12a6tm1.1Garo/Slc12a6tm1.1Garo involves: 129 * C57BL/6	abnormal axon morphology	J:183239
	abnormal corpus callosum morphology	J:183239
	abnormal locomotor behavior	J:183239
	abnormal nervous system morphology	J:183239
	abnormal sciatic nerve morphology	J:183239
	abnormal startle reflex	J:183239
	axon degeneration	J:183239
	decreased body weight	J:183239
	decreased chemical nociceptive threshold	J:183239
	decreased corpus callosum size	J:183239
	demyelination	J:183239
	impaired coordination	J:183239
	increased brain weight	J:183239
	increased locomotor activity	J:183239
	infertility	J:183239
	limb grasping	J:183239
Slc12a6tm1.1Tjj/Slc12a6tm1.1Tjj Tg(Pcp2-cre)2Mpin/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal nervous system phenotype	J:181930
Slc12a6tm1Dlp/Slc12a6+ involves: 129 * C57BL/6J	decreased exploration in new environment	J:79870
	decreased prepulse inhibition	J:79870
	normal nervous system phenotype	J:79870
Slc12a6tm1Dlp/Slc12a6tm1Dlp involves: 129 * C57BL/6J	abnormal axon morphology	J:79870
	abnormal limb posture	J:79870
	abnormal myelin sheath morphology	J:79870
	abnormal myelination	J:79870
	abnormal sciatic nerve morphology	J:79870
	axon degeneration	J:79870
	decreased exploration in new environment	J:79870
	decreased prepulse inhibition	J:79870
	demyelination	J:79870
	impaired coordination	J:79870
	impaired limb coordination	J:79870
	infertility	J:79870
	limb grasping	J:79870
	normal nervous system phenotype	J:79870
	paraparesis	J:79870
Slc12a6tm1Garo/Slc12a6tm1Garo B6.129-Slc12a6tm1Garo	no abnormal phenotype detected	J:183239
Slc12a6tm1Garo/Slc12a6tm1Garo Tg(Syn1-cre)671Jxm/0 involves: 129 * C57BL/6 * CBA	abnormal axon morphology	J:183239
	abnormal locomotor behavior	J:183239
	abnormal nervous system morphology	J:183239
	abnormal sciatic nerve morphology	J:183239
	axon degeneration	J:183239
	decreased body weight	J:183239
	decreased chemical nociceptive threshold	J:183239
	decreased corpus callosum size	J:183239
	demyelination	J:183239
	impaired coordination	J:183239
	increased brain weight	J:183239
	increased locomotor activity	J:183239
	infertility	J:183239
	limb grasping	J:183239
Slc12a6tm1Tjj/Slc12a6tm1Tjj involves: 129/Sv * C57BL/6	abnormal cell physiology	J:86183
	abnormal cerebellum morphology	J:86183
	abnormal limb posture	J:86183
	abnormal optic stalk morphology	J:86183
	abnormal sciatic nerve morphology	J:86183
	akinesia	J:86183
	axon degeneration	J:86183
	cochlear ganglion degeneration	J:86183
	cochlear hair cell degeneration	J:86183
	cochlear inner hair cell degeneration	J:86183
	cochlear outer hair cell degeneration	J:86183
	deafness	J:86183
	decreased endocochlear potential	J:86183
	hippocampal neuron degeneration	J:86183
	hypertension	J:86183
	increased susceptibility to pharmacologically induced seizures	J:86183
	limb grasping	J:86183
	limp posture	J:86183
	muscle hypertonia	J:86183
	neurodegeneration	J:86183
	organ of Corti degeneration	J:86183
	peripheral nervous system degeneration	J:86183
	sensorineural hearing loss	J:86183
	spinal cord degeneration	J:86183
	type I spiral ligament fibrocyte degeneration	J:86183
	type III spiral ligament fibrocyte degeneration	J:86183
Slc12a6tm2.1Dlp/Slc12a6tm2.1Dlp involves: 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:217087
Slc12a6tm2.1Dlp/Slc12a6tm2.1Dlp Tg(Dhh-cre)1Mejr/0 involves: 129S6/SvEvTac * C57BL/6J * FVB/N	normal behavior/neurological phenotype	J:217087
Slc12a6tm2.1Dlp/Slc12a6tm2.1Dlp Tg(Eno2-cre)39Jme/0 involves: 129S6/SvEvTac * C57BL/6J * SJL	normal behavior/neurological phenotype	J:217087