Usp8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Usp8
ubiquitin specific peptidase 8
MGI:1934029

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Usp8^tm1.1Kpk/Usp8^tm1.1Kpk Tg(Mx1-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N	abnormal hepatocyte morphology	J:122732
	hepatic necrosis	J:122732
	increased circulating bilirubin level	J:122732
	increased hepatocyte apoptosis	J:122732
	jaundice	J:122732
	liver failure	J:122732
	premature death	J:122732
Usp8^tm1.2Kpk/Usp8^tm1.2Kpk involves: 129P2/OlaHsd * FVB/N	abnormal dorsal-ventral axis patterning	J:122732
	abnormal embryo development	J:122732
	abnormal heart development	J:122732
	embryonic growth retardation	J:122732
	embryonic lethality, complete penetrance	J:122732

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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