Elovl4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elovl4
ELOVL fatty acid elongase 4
MGI:1933331

42 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elovl4^tm1Kzh/Elovl4⁺ involves: C57BL/6	abnormal cone electrophysiology	J:124499
	abnormal photoreceptor outer segment morphology	J:124499
	abnormal rod electrophysiology	J:124499
Elovl4^tm1Kzh/Elovl4^tm1Kzh involves: C57BL/6	abnormal epidermis stratum corneum morphology	J:161118
	abnormal erythrocyte morphology	J:124499
	abnormal skin appearance	J:161118
	abnormal skin condition	J:161118
	decreased fetal size	J:124499
	decreased fetal weight	J:124499
	impaired skin barrier function	J:161118
	perinatal lethality	J:161118
	shiny skin	J:161118
	short forelimb	J:124499
	thin skin	J:161118
	weight loss	J:161118
Elovl4^tm1Rayy/Elovl4⁺ involves: 129 * C57BL/6J	abnormal cone electrophysiology	J:114752
	abnormal eye electrophysiology	J:114752
	abnormal eye morphology	J:114752
	abnormal fatty acids level	J:114752
	abnormal photoreceptor outer segment morphology	J:114752
	abnormal retina morphology	J:114752
	abnormal retina outer plexiform layer morphology	J:114752
	abnormal retina pigment epithelium morphology	J:114752
	retina cone cell degeneration	J:114752
	retina photoreceptor degeneration	J:114752
	retina rod cell degeneration	J:114752
	short retina rod cell outer segment	J:114752
	thin retina outer nuclear layer	J:114752
Elovl4^tm1Sie/Elovl4⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal fertility/fecundity	J:112264
	abnormal retina morphology	J:112264
	abnormal retina photoreceptor layer morphology	J:112264
	short retina rod cell outer segment	J:112264
Elovl4^tm1Sie/Elovl4^tm1Sie involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:112264
Elovl4^tm1Wked/Elovl4⁺ involves: 129S/SvEv * 129S1/Sv	abnormal retina pigment epithelium morphology	J:121481
	abnormal rod electrophysiology	J:121481
	abnormal vision	J:121481
Elovl4^tm1Wked/Elovl4^tm1Wked involves: 129S/SvEv * 129S1/Sv	abnormal epidermal layer morphology	J:121481
	abnormal epidermis stratum corneum morphology	J:121481
	abnormal synaptic vesicle exocytosis	J:277065
	abnormal synaptic vesicle number	J:277065
	impaired skin barrier function	J:121481
	lethargy	J:121481
	neonatal lethality, complete penetrance	J:121481
	reddish skin	J:121481
Elovl4^{tm2b(EUCOMM)Hmgu}/Elovl4⁺ C57BL/6N-Elovl4^{tm2b(EUCOMM)Hmgu}/H	decreased exploration in new environment	J:211773
Elovl4^{tm2b(EUCOMM)Hmgu}/Elovl4^{tm2b(EUCOMM)Hmgu} C57BL/6N-Elovl4^{tm2b(EUCOMM)Hmgu}/H	embryonic lethality prior to organogenesis	J:211773
Elovl4^tm3Kzh/Elovl4^tm3Kzh Tg(OPN1LW-cre)4Yzl/? involves: FVB/N	normal homeostasis/metabolism phenotype	J:194246
	normal vision/eye phenotype	J:194246
Elovl4^tm3Kzh/Elovl4^tm3Kzh Tg(Rho-cre)#Yzl/? Not Specified	abnormal retina rod cell morphology	J:194246
	decreased unsaturated fatty acids level	J:194246
	normal vision/eye phenotype	J:194246
Elovl4^tm3Kzh/Elovl4^tm3Kzh Tg(Rho-icre)1Ck/? involves: C57BL/6 * SJL	abnormal retina rod cell morphology	J:194246
	decreased unsaturated fatty acids level	J:194246
	normal vision/eye phenotype	J:194246

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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