Arl3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arl3
ADP-ribosylation factor-like 3
MGI:1929699

37 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arl3^{Gt(EUCJ0159b07)1.1Hmgu}/Arl3^{Gt(EUCJ0159b07)1.1Hmgu} Tg(Rho-icre)1Ck/0 involves: C57BL/6J * C57BL/6N * SJL	abnormal cone electrophysiology	J:232436
	abnormal optokinetic reflex	J:232436
	abnormal retina rod cell outer segment morphology	J:232436
	abnormal rod electrophysiology	J:232436
	decreased total retina thickness	J:232436
	retina cone cell degeneration	J:232436
	retina rod cell degeneration	J:232436
	thin retina inner nuclear layer	J:232436
Arl3^{Gt(EUCJ0159b07)1.1Hmgu}/Arl3^{Gt(EUCJ0159b07)1.1Hmgu} Tg(Six3-cre)69Frty/0 involves: C57BL/6N * DBA/2	abnormal cone electrophysiology	J:232436
	abnormal optokinetic reflex	J:232436
	abnormal photoreceptor connecting cilium morphology	J:232436
	abnormal rod electrophysiology	J:232436
	retina cone cell degeneration	J:232436
	retina degeneration	J:232436
	retina rod cell degeneration	J:232436
	short photoreceptor outer segment	J:232436
Arl3^{Gt(EUCJ0159b07)Hmgu}/Arl3^{Gt(EUCJ0159b07)Hmgu} involves: C57BL/6N	postnatal lethality, complete penetrance	J:232436
Arl3^{Gt(OST263303)Lex}/Arl3^{Gt(OST263303)Lex} involves: 129S5/SvEvBrd	abnormal bile duct development	J:107331
	abnormal bile duct morphology	J:107331
	abnormal extrahepatic bile duct morphology	J:107331
	abnormal kidney development	J:107331
	abnormal pancreas morphology	J:107331
	absent photoreceptor outer segment	J:107331
	bile duct inflammation	J:107331
	decreased body size	J:107331
	dilated gallbladder	J:107331
	dilated renal tubule	J:107331
	distended abdomen	J:107331
	enlarged kidney	J:107331
	kidney cyst	J:107331
	pancreas cyst	J:107331
	postnatal lethality, complete penetrance	J:107331
	prenatal lethality, incomplete penetrance	J:107331
	retina outer nuclear layer degeneration	J:107331
	small pancreas	J:107331
Tg(Rho-Arl3Q71L)#Visu/0 involves: 129 FVB/N	abnormal a-wave shape	J:235882
	abnormal photoreceptor inner segment morphology	J:235882
	abnormal photoreceptor outer segment morphology	J:235882
	abnormal retina morphology	J:235882
	abnormal retina outer nuclear layer morphology	J:235882
	abnormal retina rod cell morphology	J:235882
	abnormal retina rod cell outer segment morphology	J:235882
	abnormal rod electrophysiology	J:235882
	decreased a-wave amplitude	J:235882
	decreased b-wave amplitude	J:235882
	retina rod cell degeneration	J:235882

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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