Rassf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rassf1
Ras association (RalGDS/AF-6) domain family member 1
MGI:1928386

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rassf1^tm1.1Brd/Rassf1^tm1.1Brd involves: 129S7/SvEvBrd * C57BL/6	no abnormal phenotype detected	J:101369
Rassf1^tm1.1Brd/Rassf1^tm1.1Brd Tg(Myh6-cre)2182Mds/0 involves: 129S7/SvEvBrd * FVB/N	decreased response of heart to induced stress	J:165327
Rassf1^tm1.2Brd/Rassf1^tm1.2Brd involves: 129S7/SvEvBrd	cardiac fibrosis	J:165327
	cardiac hypertrophy	J:165327
	increased response of heart to induced stress	J:165327
Rassf1^tm1.2Brd/Rassf1^tm1.2Brd involves: 129S7/SvEvBrd * C57BL/6	abnormal cell physiology	J:101369
	normal immune system phenotype	J:101369
	increased adenoma incidence	J:101369
	increased incidence of tumors by ionizing radiation induction	J:101369
	increased intestinal adenocarcinoma incidence	J:101369
	increased lymphoma incidence	J:101369
	increased mortality induced by ionizing radiation	J:101369
	premature death	J:101369
Rassf1^tm1Gpp/Rassf1⁺ involves: 129S1/SvImJ * C57BL/6	increased incidence of tumors by chemical induction	J:95683
Rassf1^tm1Gpp/Rassf1⁺ involves: 129S1/SvImJ * C57BL/6	increased lung adenoma incidence	J:95683
Rassf1^tm1Gpp/Rassf1^tm1Gpp involves: 129S1/SvImJ	abnormal oval cell morphology	J:231761
	normal endocrine/exocrine gland phenotype	J:231761
	increased hepatocellular carcinoma incidence	J:231761
	increased liver adenoma incidence	J:231761
	increased liver tumor incidence	J:231761
Rassf1^tm1Gpp/Rassf1^tm1Gpp involves: 129S1/SvImJ * C57BL/6	increased B cell derived lymphoma incidence	J:95683
	increased incidence of tumors by chemical induction	J:95683
	increased lung adenoma incidence	J:95683

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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