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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Chp1
calcineurin-like EF hand protein 1
MGI:1927185
28 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Chp1em1(IMPC)Tcp/Chp1+
C57BL/6NCrl-Chp1em1(IMPC)Tcp/Tcp 		abnormal coat/ hair morphology J:211773
abnormal embryo size J:211773
decreased mean corpuscular hemoglobin J:211773
embryonic growth retardation J:211773
Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp
C57BL/6NCrl-Chp1em1(IMPC)Tcp/Tcp 		abnormal embryo size J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp
C57BL/6NCrl-Chp1em1(IMPC)Tcp/TcpMmucd 		abnormal allantois morphology J:374598
abnormal chorioallantoic fusion J:374598
abnormal embryo morphology J:374598
abnormal head shape J:374598
abnormal heart development J:374598
abnormal placenta development J:374598
abnormal placenta labyrinth morphology J:374598
abnormal trophoblast layer morphology J:374598
abnormal visceral yolk sac morphology J:374598
decreased embryo size J:374598
decreased spongiotrophoblast size J:374598
embryonic growth retardation J:374598
embryonic lethality during organogenesis, complete penetrance J:374598
failure of chorioallantoic fusion J:374598
incomplete embryo turning J:374598
incomplete rostral neuropore closure J:374598
Chp1vac/Chp1vac
B6(C3Fe)-Chp1vac 		abnormal Purkinje cell axon morphology J:199873
abnormal synaptic bouton morphology J:199873
ataxia J:199873
axon degeneration J:199873
axonal dystrophy J:199873
Purkinje cell degeneration J:199873
tremors J:199873
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory