Ppp1r15a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
MGI:1927072

17 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp1r15a^em2(IMPC)H/Ppp1r15a^em2(IMPC)H C57BL/6NTac-Ppp1r15a^em2(IMPC)H/H	decreased mean corpuscular hemoglobin	J:211773
	increased circulating alanine transaminase level	J:211773
	increased red blood cell distribution width	J:211773
Ppp1r15a^tm1.1Ajf/Ppp1r15a^tm1.1Ajf involves: 129 * C57BL/6	abnormal erythrocyte morphology	J:106905
	abnormal erythropoiesis	J:106905
	abnormal splenic cell ratio	J:106905
	acanthocytosis	J:106905
	anisopoikilocytosis	J:106905
	decreased erythrocyte osmotic fragility	J:106905
	decreased hemoglobin content	J:106905
	decreased mean corpuscular hemoglobin	J:106905
	decreased mean corpuscular volume	J:106905
	increased number of Howell-Jolly bodies	J:106905
	increased spleen weight	J:106905
	leptocytosis	J:106905
	microcytosis	J:106905
Ppp1r15a^tm1Dron/Ppp1r15a^tm1Dron involves: 129S6/SvEvTac	abnormal cell physiology	J:82255
Ppp1r15a^tm1Kii/Ppp1r15a^tm1Kii involves: 129P2/OlaHsd	abnormal cell physiology	J:110590
Ppp1r15a^tm1Kii/Ppp1r15a^tm1Kii involves: 129P2/OlaHsd	no abnormal phenotype detected	J:110590

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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