Huwe1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Huwe1
HECT, UBA and WWE domain containing 1
MGI:1926884

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^tm1(cre)Reth/Cd79a⁺ Huwe1^tm1.1Mak/Y Trp53^tm1Brn/Trp53^tm1Brn involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal class switch recombination	J:181705
	absent B-1a cells	J:181705
	decreased IgG1 level	J:181705
	decreased IgM level	J:181705
	normal immune system phenotype	J:181705
Huwe1^tm1Wgu/Y Tg(Ins2-cre)23Herr/0 Trp53^tm1Thl/Trp53^tm1Thl involves: C57BL/6J * CBA/J	normal endocrine/exocrine gland phenotype	J:182446
	normal homeostasis/metabolism phenotype	J:182446
	hyperglycemia	J:182446
	normal mortality/aging	J:182446

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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