Mvp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mvp
major vault protein
MGI:1925638

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mvp^{Gt(IST10954E2)Tigm}/Mvp⁺ C57BL/6N-Mvp^{Gt(IST10954E2)Tigm}	abnormal cingulate gyrus morphology	J:343325
	abnormal hippocampus pyramidal cell layer	J:343325
	abnormal limbic system morphology	J:343325
	decreased brain size	J:343325
	decreased cingulate cortex size	J:343325
	decreased corpus callosum size	J:343325
	decreased dentate gyrus size	J:343325
	decreased piriform cortex size	J:343325
	decreased primary motor cortex size	J:343325
	decreased secondary somatosensory cortex size	J:343325
	enlarged lateral ventricles	J:343325
	small hippocampus	J:343325
Mvp^{Gt(IST10954E2)Tigm}/Mvp^{Gt(IST10954E2)Tigm} C57BL/6N-Mvp^{Gt(IST10954E2)Tigm}	abnormal cingulate gyrus morphology	J:343325
	abnormal hippocampus neuron morphology	J:343325
	abnormal limbic system morphology	J:343325
	abnormal neuron morphology	J:343325
	normal behavior/neurological phenotype	J:343325
	decreased brain size	J:343325
	decreased corpus callosum size	J:343325
	decreased dendritic spine density	J:343325
	decreased miniature excitatory postsynaptic current amplitude	J:343325
	decreased secondary somatosensory cortex size	J:343325
	microcephaly	J:343325
	normal nervous system phenotype	J:343325
	small hippocampus	J:343325
	small thalamus	J:343325
Mvp^tm1Wie/Mvp^tm1Wie involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:80831, J:113597

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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