Ccdc88b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccdc88b
coiled-coil domain containing 88B
MGI:1925567

13 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccdc88b^em1(IMPC)Tcp/Ccdc88b^em1(IMPC)Tcp C57BL/6NCrl-Ccdc88b^em1(IMPC)Tcp/Tcp	decreased fasting circulating glucose level	J:211773
	decreased leukocyte cell number	J:211773
	decreased lymphocyte cell number	J:211773
	enlarged lymph nodes	J:211773
	polycystic kidney	J:211773
Ccdc88b^m1Pgrs/Ccdc88b^m1Pgrs involves: 129S1/SvImJ * C57BL/6J * C57BL/10J	decreased susceptibility to parasitic infection induced morbidity/mortality	J:230618
Ccdc88b^m1Pgrs/Ccdc88b^m1Pgrs involves: C57BL/6J * C57BL/10J	decreased CD8-positive, alpha-beta T cell number	J:230618
	decreased interferon-gamma secretion	J:230618
	decreased susceptibility to parasitic infection	J:230618
	decreased susceptibility to parasitic infection induced morbidity/mortality	J:230618
	decreased T cell proliferation	J:230618
	decreased tumor necrosis factor secretion	J:230618
	normal immune system phenotype	J:230618
	increased myeloid cell number	J:230618

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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