Coq6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Coq6
coenzyme Q6 monooxygenase
MGI:1924408

35 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Coq6^{tm1a(EUCOMM)Hmgu}/Coq6^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	embryonic lethality, complete penetrance	J:278754
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ B6N(Cg)-Coq6^{tm1b(EUCOMM)Hmgu}/J	increased circulating sodium level	J:211773
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/Ics	abnormal cornea morphology	J:211773
	abnormal vitreous body morphology	J:211773
	increased fasting circulating glucose level	J:211773
	persistence of hyaloid vascular system	J:211773
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6^{tm1b(EUCOMM)Hmgu} B6N(Cg)-Coq6^{tm1b(EUCOMM)Hmgu}/J	abnormal embryo size	J:211773
	abnormal forebrain development	J:211773
	abnormal tail bud morphology	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6^{tm1b(EUCOMM)Hmgu} C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773
Coq6^{tm1c(EUCOMM)Hmgu}/Coq6^{tm1c(EUCOMM)Hmgu} Tg(NPHS2-cre)295Lbh/0 involves: C57BL/6 * C57BL/6N * SJL	abnormal glomerular capillary morphology	J:278754
	abnormal mitochondrial physiology	J:278754
	abnormal podocyte morphology	J:278754
	abnormal podocyte slit junction morphology	J:278754
	albuminuria	J:278754
	decreased podocyte number	J:278754
	dilated renal tubule	J:278754
	disheveled coat	J:278754
	glomerulosclerosis	J:278754
	hunched posture	J:278754
	increased mitochondrial number	J:278754
	increased mitochondrial size	J:278754
	increased renal glomerulus basement membrane thickness	J:278754
	increased urine protein level	J:278754
	moribund	J:278754
	pale kidney	J:278754
	podocyte foot process effacement	J:278754
	premature death	J:278754
	renal cast	J:278754
	renal glomerulus fibrosis	J:278754
	renal interstitial fibrosis	J:278754
	renal tubule atrophy	J:278754
	small kidney	J:278754

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23