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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Arfgap2
ARF GTPase activating protein 2
MGI:1924288
7 phenotypes from 1 allele in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Arfgap2tm1c(EUCOMM)Hmgu/Arfgap2tm1c(EUCOMM)Hmgu
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: 129S4/SvJae * C57BL/6J * C57BL/6N * C57BL/10 * CBA/Ca
normal immune system phenotype J:363611
Arfgap2tm1c(EUCOMM)Hmgu/Arfgap2tm1c(EUCOMM)Hmgu
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * C57BL/6N
normal immune system phenotype J:363611
Arfgap2tm1c(EUCOMM)Hmgu/Arfgap2tm1c(EUCOMM)Hmgu
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
abnormal macrophage activation involved in immune response J:363611
decreased interferon-beta secretion J:363611
decreased interleukin-6 secretion J:363611
decreased level of surface class I molecules J:363611
decreased level of surface class II molecules J:363611
decreased macrophage cytokine production J:363611
normal immune system phenotype J:363611
Arfgap2tm1c(EUCOMM)Hmgu/Arfgap2tm1c(EUCOMM)Hmgu
Tg(Cd4-cre)1Cwi/0
involves: 129S4/SvJae * C57BL/6J * C57BL/6N
normal immune system phenotype J:363611

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory