Coq8b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Coq8b
coenzyme Q8B
MGI:1924139

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Coq8b^{tm1b(EUCOMM)Hmgu}/Coq8b⁺ B6N(Cg)-Coq8b^{tm1b(EUCOMM)Hmgu}/J	decreased bone mineral content	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased locomotor activity	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	impaired glucose tolerance	J:211773
Coq8b^{tm1b(EUCOMM)Hmgu}/Coq8b^{tm1b(EUCOMM)Hmgu} B6N(Cg)-Coq8b^{tm1b(EUCOMM)Hmgu}/J	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Coq8b^{tm1c(EUCOMM)Hmgu}/Coq8b^{tm1c(EUCOMM)Hmgu} Tg(NPHS2-cre)295Lbh/0 involves: C3H * C57BL/6 * C57BL/6N * SJL	abnormal coat appearance	J:294296
	abnormal podocyte morphology	J:294296
	abnormal podocyte slit junction morphology	J:294296
	decreased circulating serum albumin level	J:294296
	glomerulosclerosis	J:294296
	hunched posture	J:294296
	increased blood urea nitrogen level	J:294296
	increased circulating serum albumin level	J:294296
	increased mitochondrial number	J:294296
	increased mitochondrial size	J:294296
	kidney failure	J:294296
	pale kidney	J:294296
	podocyte foot process effacement	J:294296
	premature death	J:294296
	renal interstitial fibrosis	J:294296
	renal tubule atrophy	J:294296
	small kidney	J:294296

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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