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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rftn1
raftlin lipid raft linker 1
MGI:1923688
16 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Rftn1tm1Ayos/Rftn1tm1Ayos
B6.Cg-Rftn1tm1Ayos 		abnormal CD4-positive T cell differentiation J:150299
decreased IgG2a level J:150299
decreased interferon-gamma secretion J:150299
decreased interleukin-4 secretion J:150299
decreased interleukin-17 secretion J:150299
decreased splenocyte number J:150299
decreased susceptibility to experimental autoimmune encephalomyelitis J:150299
Tg(Lck/Emu-Rftn1)1Ayos/?
involves: C57BL/6 		increased IgG1 level J:150299
increased IgG2a level J:150299
increased IgG3 level J:150299
increased IgM level J:150299
increased interferon-gamma secretion J:150299
increased interleukin-4 secretion J:150299
increased interleukin-17 secretion J:150299
increased susceptibility to experimental autoimmune encephalomyelitis J:150299
increased T cell proliferation J:150299
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory