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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
MGI:1923385
11 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Prex2em1(IMPC)Bay/Prex2em1(IMPC)Bay
C57BL/6N-Prex2em1(IMPC)Bay/BayMmucd 		thin ventricular wall J:211773
Prex2Gt(AH0440)Wtsi/Prex2Gt(AH0440)Wtsi
B6.129P2-Prex2Gt(AH0440)Wtsi 		impaired glucose tolerance J:206382
increased circulating glucose level J:206382
insulin resistance J:206382
Prex2Gt(RRD186)Byg/Prex2Gt(RRD186)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal Purkinje cell dendrite morphology J:133335
decreased body weight J:133335
decreased locomotor activity J:133335
impaired coordination J:133335
increased startle reflex J:133335
limb grasping J:133335
short stride length J:133335
Prex2Gt(RRD186)Byg/Prex2Gt(RRD186)Byg
Tg(Pcp2-EGFP)2Yuza/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal Purkinje cell dendrite morphology J:133335
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/07/2025
MGI 6.24 		The Jackson Laboratory