Smurf1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Smurf1
SMAD specific E3 ubiquitin protein ligase 1
MGI:1923038

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Smurf1^tm1Wran/Smurf1⁺ Smurf2^tm1Wran/Smurf2^tm1Wran involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal neural tube closure	J:148693
	abnormal neural tube morphology	J:148693
	abnormal notochord morphology	J:148693
	abnormal orientation of cochlear hair cell stereociliary bundles	J:148693
	abnormal orientation of outer hair cell stereociliary bundles	J:148693
	abnormal rostral-caudal body axis extension	J:148693
	curly tail	J:148693
	exencephaly	J:148693
	perinatal lethality, incomplete penetrance	J:148693
	spina bifida	J:148693
Smurf1^tm1Wran/Smurf1^tm1Wran Smurf2^tm1Wran/Smurf2⁺ involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal notochord morphology	J:148693
	abnormal orientation of cochlear hair cell stereociliary bundles	J:148693
	abnormal orientation of outer hair cell stereociliary bundles	J:148693
	curly tail	J:148693
	exencephaly	J:148693
	perinatal lethality, incomplete penetrance	J:148693
	spina bifida	J:148693
Smurf1^tm1Wran/Smurf1^tm1Wran Smurf2^tm1Wran/Smurf2^tm1Wran involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal embryonic neuroepithelium morphology	J:148693
	abnormal gastrulation	J:148693
	abnormal gastrulation movements	J:148693
	embryonic lethality during organogenesis, complete penetrance	J:148693
	enlarged floor plate	J:148693
	open neural tube	J:148693

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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