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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rspo2
R-spondin 2
MGI:1922667
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Lrp6Gt(Ex187)Byg/\Lrp6+
\Rspo2tm1Nuv/\Rspo2tm1Nuv
involves: 129 * 129P2/OlaHsd * C57BL/6 		abnormal craniofacial morphology J:171482
cleft palate J:171482
cleft upper lip J:171482
decreased cranium height J:171482
short mandible J:171482
short maxilla J:171482
short Meckel's cartilage J:171482
\Lrp6Gt(Ex187)Byg/\Lrp6Gt(Ex187)Byg
\Rspo2tm1Nuv/\Rspo2tm1Nuv
involves: 129 * 129P2/OlaHsd * C57BL/6 		prenatal lethality, complete penetrance J:171482
\Rspo2ftls/\Rspo2ftls
\Rspo3tm1.1Jcob/\Rspo3tm1.2Jcob
\Tg(Prrx1-cre)1Cjt/0
involves: 129S6/SvEvTac * C57BL/6 * CD-1 * SJL 		abnormal digit morphology J:188812
abnormal forelimb morphology J:188812
abnormal hindlimb morphology J:188812
abnormal humerus morphology J:188812
abnormal lung morphology J:188812
abnormal scapula morphology J:188812
absent gastric milk in neonates J:188812
absent tibia J:188812
adactyly J:188812
bowed femur J:188812
brachydactyly J:188812
neonatal lethality, complete penetrance J:188812
short femur J:188812
short tibia J:188812
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory