Mei4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mei4
meiotic double-stranded break formation protein 4
MGI:1922283

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mei4^em1(IMPC)Mbp/Mei4^em1(IMPC)Mbp C57BL/6NCrl-Mei4^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged spleen	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	small kidney	J:211773
	small testis	J:211773
Mei4^tm1Bdm/Mei4^tm1Bdm involves: 129S2/SvPas	abnormal chromosomal synapsis	J:161203
	abnormal epididymis morphology	J:161203
	abnormal gametogenesis	J:161203
	abnormal internal male genitalia morphology	J:161203
	abnormal meiosis	J:161203
	abnormal ovarian follicle number	J:161203
	abnormal reproductive system morphology	J:161203
	abnormal seminiferous tubule morphology	J:161203
	abnormal spermatocyte morphology	J:276412
	abnormal synaptonemal complex	J:161203
	abnormal testis morphology	J:161203
	arrest of male meiosis	J:161203
	azoospermia	J:161203
	decreased primary ovarian follicle number	J:161203
	decreased primordial ovarian follicle number	J:161203
	decreased testis weight	J:161203
	normal embryo phenotype	J:161203
	increased testis apoptosis	J:161203

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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