Tnks2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
MGI:1921743

7 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnks2^tm1.1Susm/Tnks2⁺ involves: 129S/SvEv * C57BL/6	postnatal lethality, incomplete penetrance	J:106917
Tnks2^tm1.1Susm/Tnks2^tm1.1Susm involves: 129S/SvEv * C57BL/6	normal cellular phenotype	J:106917
	decreased body weight	J:106917
	postnatal lethality, incomplete penetrance	J:106917
Tnks2^tm1.1Yjc/Tnks2^tm1.1Yjc involves: 129S1/Sv	normal cellular phenotype	J:106918, J:137985
	decreased adipocyte glucose uptake	J:137985
	decreased body weight	J:106918, J:137985
	normal mortality/aging	J:106918
Tnks2^{tm1b(KOMP)Wtsi}/Tnks2^{tm1b(KOMP)Wtsi} C57BL/6N-Tnks2^{tm1b(KOMP)Wtsi}/J	increased grip strength	J:211773
	increased startle reflex	J:211773
Tnks2^tm1Susm/Tnks2^tm1Susm involves: 129S/SvEv * C57BL/6	normal cellular phenotype	J:106917
	decreased body weight	J:106917
	postnatal lethality, incomplete penetrance	J:106917

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