Arhgap18 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgap18
Rho GTPase activating protein 18
MGI:1921160

19 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgap18^{tm1a(KOMP)Wtsi}/Arhgap18^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Arhgap18^{tm1a(KOMP)Wtsi}/Wtsi	increased body length	J:175295
	increased circulating calcium level	J:175295
Arhgap18^{tm1a(KOMP)Wtsi}/Arhgap18^{tm1a(KOMP)Wtsi} C57BL/6-Arhgap18^{tm1a(KOMP)Wtsi}	abnormal abdominal aorta morphology	J:267328
	abnormal actin cytoskeleton morphology	J:267328
	abnormal aorta elastic tissue morphology	J:267328
	abnormal aorta tunica adventitia morphology	J:267328
	abnormal aorta tunica media morphology	J:267328
	abnormal aorta wall morphology	J:267328
	abnormal ascending aorta morphology	J:267328
	abnormal vascular smooth muscle physiology	J:267328
	normal cardiovascular system phenotype	J:267328
	decreased vasoconstriction	J:267328
	increased susceptibility to aneurysm induced morbidity/mortality	J:267328
	increased susceptibility to induced aneurysm formation	J:267328
Arhgap18^{tm1a(KOMP)Wtsi}/Arhgap18^{tm1a(KOMP)Wtsi} involves: C57BL/6N	abnormal retina blood vessel morphology	J:237445
	abnormal retina vasculature morphology	J:237445
	abnormal tumor vascularization	J:237445
	increased angiogenesis	J:237445
	increased tumor growth/size	J:237445

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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