Mark4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mark4
MAP/microtubule affinity regulating kinase 4
MGI:1920955

25 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mark4^em1(IMPC)Mbp/Mark4^em1(IMPC)Mbp C57BL/6N-Mark4^em1(IMPC)Mbp/Ucd	abnormal eye morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal uterus morphology	J:211773
	enlarged spleen	J:211773
	increased vertical activity	J:211773
	microphthalmia	J:211773
	small testis	J:211773
Mark4^Gt(XG191)Byg/Mark4^Gt(XG191)Byg B6.129P2-Mark4^Gt(XG191)Byg	decreased susceptibility to diet-induced obesity	J:192469
	decreased total body fat amount	J:192469
	increased carbon dioxide production	J:192469
	increased oxygen consumption	J:192469
	increased respiratory quotient	J:192469
Mark4^Gt(XG191)Byg/Mark4^Gt(XG191)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal glucose homeostasis	J:192469
	decreased brown fat cell lipid droplet size	J:192469
	decreased circulating cholesterol level	J:192469
	decreased circulating glucose level	J:192469
	decreased circulating insulin level	J:192469
	decreased circulating triglyceride level	J:192469
	decreased susceptibility to diet-induced obesity	J:192469
	decreased total body fat amount	J:192469
	hyperactivity	J:192469
	increased carbon dioxide production	J:192469
	increased energy expenditure	J:192469
	increased fluid intake	J:192469
	increased insulin sensitivity	J:192469
	increased oxygen consumption	J:192469
	increased respiratory quotient	J:192469
	polyphagia	J:192469

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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