Tdp1 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tdp1
tyrosyl-DNA phosphodiesterase 1
MGI:1920036

13 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tdp1^em1(IMPC)Tcp/Tdp1^em1(IMPC)Tcp C57BL/6NCrl-Tdp1^em1(IMPC)Tcp/Tcp	decreased exploration in new environment	J:211773
	decreased mean corpuscular volume	J:211773
	enlarged lymph nodes	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	increased red blood cell distribution width	J:211773
Tdp1^Gt(XD105)Byg/Tdp1^Gt(XD105)Byg involves: 129P2/OlaHsd	abnormal DNA repair	J:170077
Tdp1^Gt(XD105)Byg/Tdp1^Gt(XD105)Byg involves: 129P2/OlaHsd * 129S/SvEv	normal behavior/neurological phenotype	J:127602
	increased physiological sensitivity to xenobiotic	J:127602
Tdp1^Gt(XD105)Byg/Tdp1^Gt(XD105)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal neuron physiology	J:127605
	abnormal single-strand DNA break repair	J:127605
	normal behavior/neurological phenotype	J:127605
	decreased circulating serum albumin level	J:127605
	normal homeostasis/metabolism phenotype	J:127605
	increased physiological sensitivity to xenobiotic	J:127605
	small cerebellum	J:127605

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23