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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dis3
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
MGI:1919912
7 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Dis3tm1.1Uba/Dis3tm1.1Uba
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
abnormal B cell morphology J:302856
abnormal class switch recombination J:302856
Dis3tm1e.1(EUCOMM)Hmgu/Dis3+
C57BL/6N-Dis3tm1e.1(EUCOMM)Hmgu/Ieg
abnormal retina morphology J:211773
abnormal vitreous body morphology J:211773
impaired glucose tolerance J:211773
increased startle reflex J:211773
Dis3tm1e.1(EUCOMM)Hmgu/Dis3tm1e.1(EUCOMM)Hmgu
C57BL/6N-Dis3tm1e.1(EUCOMM)Hmgu/Ieg
preweaning lethality, complete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory