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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Brf1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
MGI:1919558
14 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Brf1tm1.1Arte/Brf1+
involves: BALB/cJ
delayed blastocyst hatching from the zona pellucida J:285667
preweaning lethality, incomplete penetrance J:285667
Brf1tm1.1Arte/Brf1tm1.1Arte
involves: BALB/cJ
embryonic lethality, complete penetrance J:285667
failure of blastocyst formation J:285667
Brf1tm1Arte/Brf1tm1Arte
Not Specified
decreased body weight J:285667
increased circulating alanine transaminase level J:285667
increased circulating alkaline phosphatase level J:285667
increased circulating bilirubin level J:285667
Brf1tm1Arte/Brf1tm1Arte
Tg(Cyp1a1-cre)1Dwi/0
involves: C57BL/6 * CBA
abnormal translation J:285667
hepatic necrosis J:285667
increased hepatocyte apoptosis J:285667
liver inflammation J:285667
small liver J:285667
Brf1tm1Arte/Brf1tm1Arte
Tg(Pdx1-cre)6Tuv/0
involves: FVB/N
normal endocrine/exocrine gland phenotype J:285667

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory