Dusp11 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dusp11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
MGI:1919352

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dusp11^{Gt(BB0198)Wtsi}/Dusp11^{Gt(BB0198)Wtsi} B6.129P2-Dusp11^{Gt(BB0198)Wtsi}	abnormal macrophage activation involved in immune response	J:301503
	normal immune system phenotype	J:301503
	increased circulating interleukin-1 beta level	J:301503
	increased circulating interleukin-6 level	J:301503
	increased circulating tumor necrosis factor level	J:301503
	increased macrophage cytokine production	J:301503
	increased susceptibility to endotoxin shock	J:301503
	increased susceptibility to induced morbidity/mortality	J:301503
Dusp11^{tm1b(EUCOMM)Wtsi}/Dusp11^{tm1b(EUCOMM)Wtsi} C57BL/6N-Dusp11^{tm1b(EUCOMM)Wtsi}/Ics	abnormal cornea morphology	J:211773
	abnormal locomotor behavior	J:211773
	decreased total retina thickness	J:211773
	increased circulating aspartate transaminase level	J:211773
	prolonged QRS complex duration	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23