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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Smim3
small integral membrane protein 3
MGI:1917088
23 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd74tm1Anjm/Cd74+
Lmo2tm2(cre)Thr/Lmo2+
Smim3tm1Anjm/Smim3+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal bone marrow morphology J:155870
decreased erythrocyte cell number J:155870
decreased erythroid progenitor cell number J:155870
decreased granulocyte monocyte progenitor cell number J:155870
decreased hematopoietic stem cell number J:155870
decreased megakaryocyte-erythroid progenitor cell number J:155870
increased mean corpuscular volume J:155870
thrombocytopenia J:155870
Smim3tm1Anjm/Smim3+
Cd74tm1Anjm/Cd74+
involves: 129P2/OlaHsd * C57BL/6 		normal hematopoietic system phenotype J:155870
Smim3tm1Anjm/Smim3+
Cd74tm1Anjm/Cd74+
Lmo2tm2(cre)Thr/Lmo2+
involves: 129P2/OlaHsd * C57BL/6 		abnormal blood cell morphology J:155870
abnormal bone marrow cell number J:155870
abnormal common myeloid progenitor cell morphology J:155870
abnormal erythropoiesis J:155870
abnormal mast cell morphology J:155870
abnormal megakaryocyte morphology J:155870
abnormal megakaryocyte progenitor cell morphology J:155870
decreased bone marrow cell number J:155870
decreased erythrocyte cell number J:155870
decreased erythroid progenitor cell number J:155870
decreased granulocyte monocyte progenitor cell number J:155870
decreased granulocyte number J:155870
decreased hematopoietic stem cell number J:155870
decreased hemoglobin content J:155870
decreased megakaryocyte-erythroid progenitor cell number J:155870
decreased monocyte cell number J:155870
increased mean corpuscular volume J:155870
increased red blood cell distribution width J:155870
macrocytic anemia J:155870
macrocytosis J:155870
thrombocytopenia J:155870
Smim3tm1Anjm/Smim3+
Cd74tm1Anjm/Cd74+
Lmo2tm2(cre)Thr/Lmo2+
Trp53tm1Brd/Trp53+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		decreased erythrocyte cell number J:155870
decreased erythroid progenitor cell number J:155870
decreased granulocyte monocyte progenitor cell number J:155870
decreased hematopoietic stem cell number J:155870
decreased megakaryocyte-erythroid progenitor cell number J:155870
increased mean corpuscular volume J:155870
thrombocytopenia J:155870
Smim3tm1Anjm/Smim3+
Cd74tm1Anjm/Cd74+
Lmo2tm2(cre)Thr/Lmo2+
Trp53tm1Brd/Trp53tm1Brd
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		normal hematopoietic system phenotype J:155870
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory