Tnfsf13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfsf13
tumor necrosis factor (ligand) superfamily, member 13
MGI:1916833

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnfsf13^tm1Ash/Tnfsf13^tm1Ash B6.129-Tnfsf13^tm1Ash	no abnormal phenotype detected	J:87680
Tnfsf13^tm1Geha/Tnfsf13^tm1Geha involves: 129S4/SvJae	abnormal class switch recombination	J:88910
	decreased IgA level	J:88910
	decreased IgM level	J:88910
	normal immune system phenotype	J:88910
	increased IgG level	J:88910
	increased memory T cell number	J:88910
	increased spleen germinal center number	J:88910
	increased spleen germinal center size	J:88910
Tnfsf13^tm1Pod/Tnfsf13⁺ B6.Cg-Tnfsf13^tm1Pod	decreased IgA level	J:141374
Tnfsf13^tm1Pod/Tnfsf13^tm1Pod B6.Cg-Tnfsf13^tm1Pod	abnormal interleukin secretion	J:141374
	decreased IgA level	J:141374
	decreased IgG2a level	J:141374
	decreased interleukin-10 secretion	J:141374
	decreased interleukin-17 secretion	J:141374
	decreased susceptibility to induced arthritis	J:141374
	increased IgG1 level	J:141374
	increased interferon-gamma secretion	J:141374
	increased interleukin-4 secretion	J:141374
	increased interleukin-5 secretion	J:141374
	increased interleukin-13 secretion	J:141374
	increased interleukin-17 secretion	J:141374
	increased T cell proliferation	J:141374

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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