Letmd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Letmd1
LETM1 domain containing 1
MGI:1915864

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Letmd1^{em1(IMPC)Kmpc}/Letmd1^{em1(IMPC)Kmpc} C57BL/6NTac-Letmd1^{em1(IMPC)Kmpc}/Kmpc	decreased bone mineral density	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	increased fasting circulating glucose level	J:211773
	increased freezing behavior	J:211773
	increased heart weight	J:211773
	increased total body fat amount	J:211773
Letmd1^em1Mbp/Letmd1^em1Mbp C57BL/6J-Letmd1^em1Mbp	abnormal beige fat cell physiology	J:321533
	abnormal brown adipose tissue physiology	J:321533
	abnormal brown adipose tissue thermogenesis	J:321533
	abnormal oxygen consumption	J:321533
	decreased body surface temperature	J:321533
	decreased energy expenditure	J:321533
	decreased susceptibility to xenobiotic induced hyperthermia	J:321533
	hepatic steatosis	J:321533
	normal homeostasis/metabolism phenotype	J:321533
	impaired adaptive thermogenesis	J:321533
	impaired glucose tolerance	J:321533
	increased body fat mass	J:321533
	increased liver weight	J:321533
	increased susceptibility to diet-induced obesity	J:321533
	insulin resistance	J:321533
	whitened brown adipose tissue morphology	J:321533

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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