Rraga Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rraga
Ras-related GTP binding A
MGI:1915691

23 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ Rraga^tm2Dmsa/Rraga^tm2Dmsa involves: 129S/SvEv * 129S4/SvJae * C57BL/6	abnormal intestine apoptosis	J:213516
	decreased B cell number	J:213516
	enlarged spleen	J:213516
	increased apoptosis	J:213516
	increased lymphoma incidence	J:213516
	increased monocyte cell number	J:213516
	myeloid hyperplasia	J:213516
	premature death	J:213516
	weight loss	J:213516
Rraga^tm1.1Dmsa/Rraga^tm1.1Dmsa involves: 129 * C57BL/6 * C57BL/6J	abnormal autophagy	J:194401
	abnormal circulating amino acid level	J:194401
	abnormal gluconeogenesis	J:194401
	abnormal glycogen homeostasis	J:194401
	decreased birth weight	J:194401
	normal homeostasis/metabolism phenotype	J:194401
	hypoglycemia	J:194401
	increased susceptibility to induced morbidity/mortality	J:194401
	neonatal lethality, complete penetrance	J:194401
Rraga^tm1Dmsa/Rraga^tm1Dmsa involves: 129 * C57BL/6	decreased embryo size	J:213516
	embryonic lethality during organogenesis, complete penetrance	J:213516
	open neural tube	J:213516
Rraga^tm2.1Dmsa/Rraga^tm2.1Dmsa involves: 129S4/SvJae * C57BL/6	decreased embryo size	J:213516
	embryonic lethality during organogenesis, complete penetrance	J:213516
	open neural tube	J:213516
Rraga^tm2Dmsa/Rraga^tm2Dmsa Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S4/SvJae * C57BL/6 * DBA	decreased circulating glucose level	J:213516
	increased insulin sensitivity	J:213516

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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