Prrc2a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prrc2a
proline-rich coiled-coil 2A
MGI:1915467

17 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prrc2a^tm1Fcw/Prrc2a^tm1Fcw Olig2^{tm2(TVA,cre)Rth}/Olig2⁺ involves: 129 * C57BL/6	abnormal brain morphology	J:301796
	abnormal corpus callosum morphology	J:301796
	decreased body weight	J:301796
	decreased grip strength	J:301796
	decreased oligodendrocyte number	J:301796
	decreased oligodendrocyte progenitor number	J:301796
	dysmyelination	J:301796
	enlarged lateral ventricles	J:301796
	impaired coordination	J:301796
	impaired spatial learning	J:301796
	increased brain weight	J:301796
	normal nervous system phenotype	J:301796
	premature death	J:301796
Prrc2a^tm1Fcw/Prrc2a^tm1Fcw Tg(Gfap-cre)77.6Mvs/0 involves: BALB/c * C57BL/6NHsd	normal nervous system phenotype	J:301796
Prrc2a^tm1Fcw/Prrc2a^tm1Fcw Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	abnormal astrocyte physiology	J:301796
	abnormal brain development	J:301796
	abnormal brain morphology	J:301796
	abnormal corpus callosum morphology	J:301796
	decreased astrocyte number	J:301796
	decreased body weight	J:301796
	decreased grip strength	J:301796
	decreased nerve conduction velocity	J:301796
	decreased oligodendrocyte number	J:301796
	decreased oligodendrocyte progenitor number	J:301796
	dysmyelination	J:301796
	enlarged lateral ventricles	J:301796
	impaired coordination	J:301796
	impaired spatial learning	J:301796
	increased brain weight	J:301796
	premature death	J:301796

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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