Itfg2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itfg2
integrin alpha FG-GAP repeat containing 2
MGI:1915450

18 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itfg2^em1(IMPC)J/Itfg2⁺ C57BL/6NJ-Itfg2^em1(IMPC)J/Mmjax	increased mean corpuscular hemoglobin concentration	J:211773
Itfg2^em1(IMPC)J/Itfg2⁺ C57BL/6NJ-Itfg2^em1(IMPC)J/Mmjax	iris synechia	J:211773
Itfg2^em1(IMPC)J/Itfg2^em1(IMPC)J C57BL/6NJ-Itfg2^em1(IMPC)J/Mmjax	preweaning lethality, incomplete penetrance	J:211773
Itfg2^{Gt(OST215121)Lex}/Itfg2^{Gt(OST215121)Lex} involves: 129S5/SvEvBrd * C57BL/6J	abnormal B cell activation	J:205951
	abnormal humoral immune response	J:205951
	abnormal splenocyte physiology	J:205951
	decreased B cell number	J:205951
	decreased IgE level	J:205951
	decreased IgG1 level	J:205951
	decreased IgG2a level	J:205951
	decreased IgG2b level	J:205951
	decreased IgG3 level	J:205951
	decreased lymphocyte cell number	J:205951
	decreased spleen germinal center number	J:205951
	decreased T follicular helper cell number	J:205951
	normal immune system phenotype	J:205951
	increased B cell number	J:205951
	spleen hyperplasia	J:205951

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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